What Causes of SGOT and SGPT indicator increase?

13 06 2009

Yup,that was a usual question that faced by medical practitioner and also by patient that has it. Patient usually comes to emergency room (ER) with symptom nausea, vomiting, malaise, dehidrate mild or severe, could be jaundice in chronic or acute condition, high blood pressure, headache, etc. But the primary symptom usually vomiting that made the patient dehidration and can directly make the family as the reason to bring him to the ER in the hospital.

The disease that have relation with the increse of SGOT and SGPT are hepatitis can be viral or non viral, fatty liver, gall stone, cholecystitis, cholelithiasis, malignancy, etc. all the disease can be figure out by seeing the symptom firstly. Next to confirm the diagnosis usually doctor needs to do physical examination, may be he can find hepatomegaly, spleenomegaly, or other sign that support the diagnosis. Furthermore he will have laboratory result to compare the differential diagnosis to confirm the final diagnosis.

SGOT is usually a marker for chronic liver disease. SGOT is an enzyme that located in heart muscle, smooth muscle, liver cells, etc. SGPT is usually as a marker for acute liver disease. SGPT only located in liver cells. So if the ratio of SGOT to SGPT is high, we need pay attention that it can be chronic liver disease. And than so does otherwise if ratio SGPT to SGOT is high.

In this era, the higher rates according my opinion is fatty liver. Because nowadays people are less to do sport and like to eat fastfood, while on fastfood there were high cholesterol and if body difficult to convert it. The cholesterol will circulate around your body through the blood. So on the lab test the lipid profile show high level (high LDL, trygliseride,and  total cholesterol.but low HDL). LDL was bad cholesterol, while HDL is a good cholesterol. If the cholesterol to much in our body it can be deposit through all your body but if the lipid deposit in your liver it can cause fatty liver. Fatty liver is a condition where the surface and inside your liver cover by lipid. Sometimes lipid can kill the healthy liver cell, so that makes lab test for SGOT and SGPT increased.

The therapy for fatty liver actually first to have diet. To maintain the condition patient used to have sport, mild sport. Because patient have weak condition and they can`t be force  to do heavy sport. If they do heavy sport it will make patient condition deteriorate.

So keep healthy by diet, sport and eat healthy food. Avoid to eat fastfood or junk food. (©Ajib 2009)




67 responses

27 08 2012
sanchita roy choudhury

i m 30yrs old. my blood reports show that my hb-7%,neutrophil-76%,lymphocyte-19%,rbc-3.6,mcv-68.3,mch-19.3,mchc-28.d,rdw-17,retic count-2.25%,sgot-112,sgpt-91,iron-19,ferritin-20,tibc-403,transferin saturation-4.7% now my question is what is wrong with me?what is the disease?

30 08 2012

see a doctor

4 07 2015

Hello sir,
I am 25 years old and my SGPT is 200 .its increasing quickly. Is there any need for liver biopsy? What type of disease I have and how much is it crtical? Please advice

16 03 2013

Sir ….the blood report u have shown…show the symptoms oh major disease…..so I suggest u to consult to doctoras soon as possible……

2 06 2013

It shows that your liver has acute infection. You also had anemia. So please consult with your doctor

3 03 2016

Sir my SGPT is running just double of normal range from last 10 year. Sir what will be happen in my body and what can i do.

9 10 2012

my sgot and sgpt is high rest thing is ok then let me what should i do for diet or medicine

29 11 2012

nothing.. Enjoy life….

13 02 2016

Hello Sir.. im 15 yrs old.. My SGPT is 174.9 and SGOT is 219.9.. what do i need to do now?

2 03 2013
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26 03 2013

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2 06 2013

Thank you for the time

12 06 2013

I’m 26 years. My details are as follows. BILIRUBIN TOTAL 0.69mg/dL, BILIRUBIN DIRECT .14mg/dL, SGOT 138.1IU/L, SGPT 326.4 IU/L URIC ACID 10.28mg/dL. Taken toomuch alchohol every day. ccan anyone tell this situation???

13 06 2013

Quit Alchohol. Consult doctor immediately… he may prescribe medicines for liver and kidneys

20 06 2013

sir, my age is 21 yrs. my sgpt is 145 & sgot is 105 what should i do?

20 06 2013

if sgpt become high but normal after treatment can he drink alcohol ?

10 07 2013

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26 07 2013
mon nundy (@NundyMon)

Sir,my age is 37.Dated-19 jul 2013,L.F.T report—
Bilirubin Total -0.8mg.
SGOT -102 units/l.
SGPT -255 units/l.
HDL CHOLESTEROL -26mg/100ml.
LDL CHOLESTEROL -119mg/100ml.
TRIGLYCERIDE – 238mg/100ml.
HBsAg -Non reactive.
USG -Hepatosplenomegaly.

I stop taken Alchohol.and fast food still 10 jul 2013.Dr. sujjest me ‘NUSAM-200’ Daily 2 Tabs.and loss my body weight.Ialso taken ‘CHELIDONIUM MAJUS'(mother tincture).Please help me for to get back life.

5 09 2013

Below article says SGPT is in both liver and heart cells. Please clarify…


24 07 2014

yes you are definitely. in SGPT just indicating acute case for liver dysfunction, and SGOT indicating chronic phase for liver dysfunction

4 10 2013

bad news!
im 26 years old with 172.37 sgpt and 43.30 sgot. . what should i do to lower down the number for this? im worried =(

9 10 2013


14 01 2014

hi sir iam sov, my sgpt is very high what will I do

19 03 2014
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I am not sure the place you are getting your information, however
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4 11 2015

sir , i m 27 yrs old, my sgot 52 and sgpt 106 gamma gt 61 cholesterol 137 bilirubin totale 0.6, bilirubin directe 0. 2, lecocytes 10.5
i take alcohool occasinally , 1 or 2 times in a month, if i should take any medicine?

26 03 2014
vidhi saxena

my sgot is 68 and my sgpt is 84. I am a 16yrs old studying in class 12th. what are the various causes and reasons for this to happen ??????

13 07 2014
Urmila Singh

Siq i am 72 years old.My sgpt level is 91 and my sgot level is 138.What should i do get them normal.

24 07 2014

check ur hbsag and anti bbs level serum

17 08 2014

Sir my sgpt sgot is 195, 119 and my billurbin .8 . can u tell me i feel some pain in my lower legs. Some relasion between this

3 09 2014

sir, i am having very severe stool issue( normal stool) but daily 7-8 times.as checked by phisican found LFT test sgpt-108 & sgot 85. taking pills for lever. but how to stop motion ? as it reduces my weight my sugar level is 106 at fasting and 180 after fooding,
Please suggest how to control mys stoolissue?


25 09 2014

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Thanks foor posting when you’ve got tthe opportunity, Guess I will just book mark this page.

6 10 2014

Aw, this was a very nice post. Spending some time and actual effort to generate a very good article…
but what can I say… I hesitate a whole lot and don’t seem to get anything done.

10 10 2014


2 12 2014

Wow, wonderful weblog layout! How lengthy have you been blogging
for? you make blogging look easy. The entire glance of your web site is magnificent,
let alone the content material!

8 12 2014

Sir Sir ,
my age 26+, Sgot is 400 and Sgpt is 575. what should i do?

8 09 2016

Sir my sgpt 243 than

25 01 2015


25 01 2015


29 05 2015

Dear sir. I am 24 years my CRP is 1.2 and SGPT is 234 any suggesstion

2 06 2015

dear sir , i am 25 years old my sgpt is increase in 93.45,
please suggeste my .

2 06 2015

dear sir , i am 25 years old my sgpt is increase in 93.45,
please suggeste my

16 06 2015

i am 23yr old guy my sgpt is now 640 what should i do?

30 07 2015


my name is avinash my sgpt is 64 .i m addiction of alchohal i took every day 1 bottle of bear now i m feling very week,it is very dengerous situaton for me..??

30 07 2015

ecent 2 month before my wife got jundies (A-virus) and now she recovered with jundies (Total Billruben is 0.60)

and SGoT is 164
SGPT is 285

on last week it is SGOT is 158 and SGPT is 289
on 15 dates before SGOT is 260 and SGPT is 358
30 days before SGOT is 105 and SGPT is 117
more 45 days before SGOT is 44 and SGPT 117

prasent ALP is 140

please tell what is cause and she is taking only vegetable food

21 08 2015

I had blood checkup my sgpt 68 , sgot 52, biluribin 0.9 why? Will you please tell me what is my problem

2 09 2015

Sir my SGOT is 238 and SGPT is 132. I have stpped dringking 5 days back and is taking Nexito 5 , ursocol 300 and liv 52 nw. Will it help in a rapid reduce is the SPOT and SGPT counts. I need to undergo a medial for a new job in 2 days time..Also please caan you tell how much is the allowed ranges for these medical related to employements…Thank you

29 09 2015

Sir i am 31 years old.My sgpt level is 170 and my sgot level is 353.What should i do get them normal

19 12 2015
Rohit Srivastava

I have been tested with SGOT 65 and SGPT 94. How alarming is this? Is this due to drinking alcohol ?

8 01 2016

Hi,I am 40 years old , male, my SGOT is 40, and SGPT is 27, LDL is 312. I am a diabetic , but under control. I have fatty liver diagnosed with ultrasound.
Is this a very bad situation?, I’ve become very anxious since I got my report.

18 01 2016


Sir i am 29 years old and we had regular health checkup at our office in Liver function test my SGOT is 45.20 and SGPT is 92.80 both are higher than normal is there any risk. Do i need to consult a doctor

6 12 2016

the parameter isn’t complete yet to diagnose any illness from that data. so i suggest you to complete the result of the blood test

3 02 2016


6 12 2016

maybe you should contact the nearest internist for the medication of your illness, especially the hepatitis B

4 03 2016

I had jaundice in nov 2015. My sgpt goes upto 4400.n i was hospitalized for 9 days.but now i m feeling well…but one question is that after that report now my sgpt goes ups n downs like 114 246 79 53 n then now 134 today…my bilirubin is in normal range…0.9 mg total…what is the resaon….

6 12 2016

maybe you can ask for your doctor about that reason especially for the medicine that has been prescribe to know why your liver function decline progressively

14 06 2016


12 09 2016
Manish Garg

My daughter , now 15, suffered Necrotising pancreatistis when 10, Recovered in 6 months, since then SGOT and SGPT and LDH and CPK are high. All immune tests and Hepatitis tests are negative. All MRI of brain, thigh, eye check normal. Just now had high Lipase after 3 years. Fibroscan of Liver is Okay, What can be the issue?

6 12 2016

you can check lipid profile to make sure the wasn’t any fatty liver.

12 09 2016

Hi i’m Arvin.my SGPT is 122 and SGOT is 59, is this alarming?thank you

6 10 2016

Hi Myself Anand Sharma, My SGOTis 222 which was last year at just 61, SGPT is 447 and last year was just 154,

My total Cholesterol is 245mg/dl last year it was 230mg/dl and bad cholesterol is increased to 157 from 144, Please advise.

6 12 2016

from your liver function it shown elevated liver function and it was chronically fatty liver. but you can also do test for hbsag and anti hbs to confirm other cause for the elevated LFT. do complete check up especially for the lipid profile also

11 11 2016
Neeraj Gupta

Hi this is Neeraj here. My results are:
Bilirubin total: 1.12 mg/dL (Direct 0.40, Indirect 0.72)
SGOT: 102, SGPT: 144
HDL: 33, LDL: 111.6, VLDL: 39.4
Triglycerides: 197
C-reactive protein: 1.81

Could you please suggest what do these results indicate? I got these tests done today. However, nearly 2 months ago, my doctor told me that I have fatty liver.

Thanks in advance!

6 12 2016

from the result showed indicate fatty liver. Maybe you should try physical activity first and also use medical drugs also to maintain your health condition. hope useful

16 02 2017

My today’s Report is SGOT -101 AND SGPT — 134, As My Doctors Advice I have taken UD Liv for almost one month dose 1-0-1 since one month earlier it was 56 and 108 while tested on 23/12/2016 and 108 / 142 respectively tested on 8/12/2016 please suggest me what to do.

with regards.


12 04 2017

on 31 st March my
SGPT 282
SGOT 704
Total Bilirubin 5.72

now after a week it reached to
SGPT 1420
SGOT 1656
Total Bilirubin 11.4

my doctor is saying to do rest for 15 days, with some medicine, tell me me w how much risky is it at these levels,


11 08 2017

Hello Sir, My SGPT is 55.0 U/L and SGOT is 26.0 U/L, What should I Do?

24 10 2017

Sir, my hb: 17.2, esr: 20, sgot 48, hdl cholestrol 65, ldl 135 . I am 45. what shoould I do ?

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